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Polyphyllin III

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Product Overview
Product Name Polyphyllin III
CAS19057-60-4
FormulaC45H72O16
MW869.04
Appearance 白色粉末
Melting point288 °C (decomp)
PKa12+-.0.70 | Condition: Most Acidic Temp: 25 °C
Product details

WKQ-0000525

中文名称:重楼皂苷III

中文别名:薯蓣皂苷/薯蓣皂甙

英文名称:Polyphyllin III

英文别名:Dioscin (6CI,7CI,8CI);(3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside;(+)-Dioscin;3-O-β-D-α-L-Rhamnopyranosyl(1→4)-[α-L-rhamnopyranosyl(1→2)]-β-D-glucopyranoside-diosgenin;Collettiside III;Dioscine;Diosgenin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside;Diosgenin 3-O-α-L-rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside;Diosgenin bis-α-L-rhamnopyranosyl-(1→2 and 1→4)-β-D-glucopyranoside;Paris III;Parissaponin III;Polyphyllin III;

分子式:C45H72O16

分子量:869.04

CAS号:19057-60-4

纯度:HPLC≥98%

熔点:288 °C (decomp)

密度:1.39±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr

酸系度数:12+-.0.70 | Condition: Most Acidic Temp: 25 °C

储存条件:-20℃,干燥、避光、密封

规格:5mg10mg20mg50mg100mg500mg1g2g等应客户需求包装

供应单位:四川省维克奇生物科技有限公司

供应电话:028-81700200/4008005713

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Related literature
A novel α-L-Rhamnosidase renders efficient and clean production of icaritin
Source:SCI:Journal of Cleaner Production Author:Leiyu Cheng Notes:影响因子:9.297
Reference description

Epimedin C, icariin, icaritin dirhamnoside, baohuoside I, rutin, isoquercitrin, neohesperidin, glucohesperetin, naringin, prunin, myricetrin, myricetin, vitexin, dioscin, zingiberensis newsaponin, ginsenoside Rg2, and ginsenoside Re were all purchased from Sichuan Weikeqi Biotechnology Co., Ltd (China).

Efficient enzyme-catalyzed production of diosgenin: inspired by the biotransformation mechanisms of steroid saponins in Talaromyces stollii CLY-6
Source:SCI:GREEN CHEMISTRY Author:Leiyu Cheng Notes:影响因子:10.182
Reference description

Dried tubers of Dioscorea zingiberensis C.H. Wright (DZW, Fig. 1b; powder form, P-DZW, Fig. 1c) and crude extract of DZW (E-DZW, Fig. 1d) were supplied by Zunyi City Bei Yuan Chemical Co., Ltd (China). The standard materials of diosgenin, zingiberensis newsaponin (S1), deltonin (S2), prosapogenin A (S3), trillin (S6), polyphyllin I, and dioscin were purchased from Sichuan Weikeqi Biotechnology Co., Ltd (China). Diosgenin triglucoside (S4) and diosgenin diglucoside (S5) were purified from E-DZW. All other chemicals and reagents were of analytical grade and purchased from Beijing Chemical Co., Ltd (China).

Drug interaction study of natural steroids from herbs specifically toward human UDP-glucuronosyltransferase (UGT) 1A4 and their quantitative structure activity relationship (QSAR) analysis for prediction
Source:SCI:PHARMACOLOGICAL RESEARCH Author:Min Xu Notes:影响因子:4.816
Reference description

hecogenin (1), diosgenin (2), ruscogenin (3), gitogenin (4), tigogenin (5), solasodine (6), (24S,25S)-3β, 24-di-hydroxy-5α-spirostan (7), dracaenol C (8), 25(27)-dehydroruscogenin (9), (1β, 3β, 14α, 15α, 20R, 22S, 25R)-spirost-5-ene-tetrol (10), peimine (11), peiminine (12), peimisine (13), isoverticine (14), trillin (15), polyphyllin VI (16), polyphyllin VII (17), pallidifloside D (18), prosapogenin A (19), spongipregnoloside A (20), dioscin(21), solasonine (22), solamargine (23), gracillin (24), polyphyllin I(25), timosaponin BII (26), timosaponinA-III(27), ophiopogonin D (28), protobioside (29), (22S,25S)-26-O-β-d-glucopyranosyl-22,25-epoxyfurost-5-en-3β,26-diol-3-O-α-l-rha-mnopyranosyl(1 → 2)-β-d-gluc (30), pallidifloside E (31), parispseudoside (32), methylprotodioscin (33), protodioscin (34), pseudoprotodioscin (35), YS-IX (36), pallidifloside A (37), pallidifloside H (38), digoxin (39), bisdigoxigenin (40), 7β, 14α, 21-tri-hydroxy-diosgenin (41), 12β,14α,21-tri-hydroxy-diosgenin (42), and 11β,14α-di-hydroxyldiosgenin (43) were purchase from Sichuan weikeqi biotechnology company (Sichuan province, China). Pooled human liver microsomes (HLMs, 20 mg/mL) and pooled human primary hepatocytes were purchased from Rild Research Institute for LiverDiseases (Shanghai, China).

Pseudoprotodioscin inhibits SREBPs and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides
Source:SCI:FITOTERAPIA Author:Yanan Gai Notes:影响因子:2.431
Reference description

for the Control of Pharmaceutical and Biological Products (Beijing, China) (Fig. 1a). Dioscin (DC), pseudoprotodioscin (PPD) and methylprotodioscin (MP) were bought from Sichuan Weikeqi Biological Technology Co. Ltd. (Sichuan, China) (Fig. 1a).

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